Downtown Sioux Falls

Commercial Real Estate Listings

If you are looking for a great commercial space in the heart of the city, take a look at the variety of the properties listed below. For more information on available spaces for sale or lease, contact these Real Estate Agencies.

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Willey-Williams Building – Suite 302 – 1,203 SF – Office For Lease

Willey-Williams Building – Suite 302 – 1,203 SF – Office For Lease

Located at the prominent corner of 6th Street and Main Avenue, this historic property offers a unique opportunity to lease space within the beautifully preserved Willey & Williams Building. The building underwent a major restoration in 1985 and today features a mix of professional office and commercial space. The suite includes three+ spacious private offices, large kitchenette, multiple storage areas, original hardwood flooring and abundant natural light. There are 2 assigned underground parking spaces included with additional surface parking available for lease.
$1,510 / mo.
1203 sq. ft. Negotiable
330 N. Main Avenue
Sioux Falls, SD 57104
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Willey & Williams Building – Suite 203 – 1,004 SF – Office For Lease

Willey & Williams Building – Suite 203 – 1,004 SF – Office For Lease

Located at the prominent corner of 6th Street and Main Avenue, this historic property offers a unique opportunity to lease space within the beautifully preserved Willey's & Williams Building. The building underwent a major restoration in 1985 and today features a mix of professional office and commercial space. There are four+ spacious private offices, abundant storage, and large windows providing natural light. There are two assigned underground parking spaces that come with the suite, with additional surface parking available for lease.
$1,256 / mo.
1004 sq. ft. Negotiable
330 N. Main Avenue
Sioux Falls, SD 57104
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Harvester Building – Suite 202 – 2,774 SF Office For Lease

Harvester Building – Suite 202 – 2,774 SF Office For Lease

This suite can be configured into an open workspace with fireplace, in addition to 2 private offices, large storage closet, full kitchen, full private bath, washer and dryer hookup. The building offers a workout area, patio spaces, and access to shopping and dining.This versatile commercial space offers an excellent opportunity for retail, office, medical, or professional service users seeking a well-located property with competitive lease terms in a desirable location.
$3,629.32 / mo.
2774 sq. ft. Negotiable
196 E. 6th Street, Suite 202
Sioux Falls, SD 57104
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Maxwell Building – Suite 1 – 1,500 SF OFFICE/RETAIL FOR LEASE

Maxwell Building – Suite 1 – 1,500 SF OFFICE/RETAIL FOR LEASE

Beautiful and Bright Space in the Historic Nolen Building. Extensive renovations completed in 2009. This 1,500 square foot space is an open floor plan with tall ceilings, carpeted floors, and raised area in the front for a conference room, large office, or display. There are shared bathrooms and an opportunity for storage in the lower level. Great signage and visibility in the unique storefront space which offers a wide range of possibilities. There is an on site shared parking lot, street parking directly in front of the building, and city leased parking nearby.
$2,234 / mo.
1500 sq. ft. Negotiable
319 N. Main Avenue, Suite 1
Sioux Falls, SD 57104
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Randolph Building – Suite C – 2,448 SF Office For Lease

Randolph Building – Suite C – 2,448 SF Office For Lease

Downtown Office Space for lease at the corner of historic 6th and Main.​ This second floor office space has been beautifully remodeled with respect to it’s historic features.​ There are four executive offices plus a conference room.​ Two private restrooms and a large kitchen/break area.​ Multiple storage rooms and a wide open work area.​
$3,468 / mo.
2,448 sq. ft. $12/sq. ft. Negotiable
320 N. Main Avenue
Sioux Falls, SD 57104
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Stockman’s Building – 8th & Weber – 340 SF Office Suite For Lease

Stockman’s Building – 8th & Weber – 340 SF Office Suite For Lease

Located in the heart of Sioux Falls' vibrant and rapidly growing East Bank District, this beautifully restored historic property occupies the prominent corner of 8th Street and Weber Avenue. The building offers excellent walkability to downtown Sioux Falls and is surrounded by popular restaurants, coffee shops, and local amenities.
$450 / mo.
340 sq. ft. Negotiable
201 N. Weber Avenue
Sioux Falls, SD 57104
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The Switchyard on 8th Street

The Switchyard on 8th Street

Position your business in the heart of downtown Sioux Falls’ East Bank, one of the region’s fastest growing and most dynamic areas. This Class A retail and office development offers four available floors with flexible, customizable floor plans, including full floor opportunities of up to approximately 12,000 square feet.
4,700-12,000 sq. ft. $30/sq. ft. NNN
455 E. 8th Street
Sioux Falls, SD 57103
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River Centre – 4th Floor

River Centre – 4th Floor

Elevate your business with a premier office space overlooking the Big Sioux River in the heart of downtown Sioux Falls.
12909 sq. ft. $18.50/sq. ft. NNN
200 E. 10th Street
Sioux Falls, SD 57104
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Cherapa Place I- 3rd Floor

Cherapa Place I- 3rd Floor

Discover a move‑in‑ready, modern office space at Cherapa Place I with stunning river views, sleek furnishings, and premium amenities that make upgrading your workspace feel effortless.
9837 sq. ft. $21.50/SF NNN/sq. ft. Term Thru 10/31/2027
300 N. Cherapa Place
Sioux Falls, SD 57103
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Dakota Avenue Building

Dakota Avenue Building

Unique property available in historic downtown Sioux Falls.
$1,750,000
13,200 SF sq. ft.
106 S Dakota Ave
Sioux Falls, SD 57104
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Weber Properties

Weber Properties

Portfolio of industrial properties across from Falls Park in a prime redevelopment location
$5,000,000
34965 sq. ft.
712-838 North Weber Avenue
Sioux Falls, SD 57103
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Cherapa Place – Suite 502

Cherapa Place – Suite 502

Versatile 5th Floor office sublease space in Cherapa Place on the East Bank of downtown Sioux Falls
5847 sq. ft. $$24.00/ sq. ft./sq. ft.
300 North Cherapa Place, Suite 502
Sioux Falls, SD 57103
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First Dakota Building – Suite 308 & 310

First Dakota Building – Suite 308 & 310

Conveniently located on Main Street in downtown Sioux Falls.
1,517 sq. ft. $20/sq. ft.
101 N Main Ave
Sioux Falls, SD 57104
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Rock Island – Suite 140

Rock Island – Suite 140

Multiple amenities nearby, including boutiques, dining establishments, coffee shops, hotels, and services.
1,524 sq. ft. $15/sq. ft.
300 N Phillips Ave
Sioux Falls, SD 57104
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300 Building – Suite 411

300 Building – Suite 411

Conveniently located near downtown shopping and restaurants.
$450 / mo.
431 sq. ft.
300 N Dakota Ave
Sioux Falls, SD 57104
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Cherapa Place – 2nd Floor

Cherapa Place – 2nd Floor

Versatile office space located on the 2nd floor of Cherapa Place on the East Bank of downtown Sioux Falls.
14,358 sq. ft. $23/sq. ft.
300 N Cherapa Pl
Sioux Falls, SD 57103
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Historic Security National Building – Third Floor Salon/Office Space F

Historic Security National Building – Third Floor Salon/Office Space F

Beautiful, historic building in the heart of downtown Sioux Falls.
$850 / mo.
500 sq. ft.
101 S Main Ave
Sioux Falls, SD 57104
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Steel District Retail Space

Steel District Retail Space

Experience the best shopping and dining destination that Sioux Falls has to offer.
1,002 - 1,580 sq. ft. $25/sq. ft.
196 1/2 E 6th St
Sioux Falls, SD 57104
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Reid Street Building

Reid Street Building

Exciting opportunity to lease a stand-alone building just south of 8th & Railroad and the Lumber Exchange Building.
3,109 sq. ft. $19.30/sq. ft.
114 S Reid St
Sioux Falls, SD 57103
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Argus Leader Building

Argus Leader Building

Excellent location on the corner of Minnesota Avenue and 10th St.
99,072 sq. ft.
200 S Minnesota Ave
Sioux Falls, SD 57104
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Tract 121 Flex Space

Tract 121 Flex Space

Unique flex space opportunity located in the East Bank sector near downtown Sioux Falls.
2,496 sq. ft. $8.50/sq. ft.
121 S Franklin Ave
Sioux Falls, SD 57103
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Downtown Flex Space

Downtown Flex Space

Unique historic property available in downtown Sioux Falls.
13,200 sq. ft. $8.50/sq. ft.
106 S Dakota Ave
Sioux Falls, SD 57104
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300 Building – Suite 306

300 Building – Suite 306

Prominent location with great views of downtown.
1,260 sq. ft. $12.38/sq. ft.
300 N Dakota Ave
Sioux Falls, SD 57104
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Historical Security National Building – Third Floor Salon/Office Space A

Historical Security National Building – Third Floor Salon/Office Space A

Beautiful, historic building in the heart of downtown Sioux Falls.
$550 / mo.
250 sq. ft.
101 S Main Ave
Sioux Falls, SD 57104
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Historical Security National Building – Third Floor Office Space 302

Historical Security National Building – Third Floor Office Space 302

Beautiful, historic building in the heart of downtown Sioux Falls.
1,038 sq. ft. $17-$19/sq. ft.
101 S Main Ave
Sioux Falls, SD 57104
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Huey Office Building – Suite 120

Huey Office Building – Suite 120

Office space located in the Huey Building in the heart of downtown Sioux Falls.
2,400 sq. ft. $10/sq. ft.
120 N Phillips Avenue, Ste 120
Sioux Falls, SD 57104
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Cherapa Place – Building IV – First Floor

Cherapa Place – Building IV – First Floor

Perfect for restaurant, personal services, boutiques shops.
10,350 sq. ft. $25/sq. ft.
301 N Reid Place
Sioux Falls, SD 57103
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Cherapa Place – Building II – Second Floor

Cherapa Place – Building II – Second Floor

Beautiful views of the Big Sioux River, the Arc of Dreams and downtown Sioux Falls.
8,834 sq. ft. $25/sq. ft.
345 N Reid Place
Sioux Falls, SD 57103
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Cherapa Place – Building III – First Floor

Cherapa Place – Building III – First Floor

12,000 sq. ft. $25/sq. ft.
350 N Reid Place
Sioux Falls, SD 57103
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Cherapa Place – Building II – First Floor

Cherapa Place – Building II – First Floor

Beautiful views of the Big Sioux River, the Arc of Dreams and downtown Sioux Falls.
22,370 sq. ft. $25/sq. ft.
345 N Reid Place
Sioux Falls, SD 57103
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Steel District Office Development

Steel District Office Development

The Sioux Steel Development will showcase the upper level of The Falls located in the Uptown Development of Sioux Falls.
2,683 - 16,697 sq. ft. $26 - $30/sq. ft.
196 1/2 E 6th St
Sioux Falls, SD 57104
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The Plaza

The Plaza

Be part of the downtown vibrancy and professional tenant mix at The Plaza!
3,968 sq. ft. $8 SF Gross + Utilities/sq. ft.
101 S Phillips Ave
Sioux Falls, SD 57104
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